Best Medicine
FOX's American remake of Doc Martin transplants the grumpy surgeon to the fishing village of Port Wenn, and the results are exactly as mixed as every transatlantic comedy transplant before it. Josh Charles plays Dr. Martin Best, a brilliant Boston surgeon who flees to the small coastal town where he spent childhood summers, only to discover he has developed a phobia of blood, which is a problem for a country doctor. The premise survives the move; the tone is the question.
Cast & Key People
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Our Review
Cast & Key People
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Our Review
Best Medicine (2026) is a comedy and drama series from FOX. It has built a run of 13 episodes at roughly 60 minutes each. It premiered on January 4, 2026. Viewers rate it 6.1 out of 10. It is currently running. It runs 2 seasons.
What Best Medicine Is About
In Best Medicine a brilliant surgeon leaves Boston to become a small-town doctor where he spent childhood summers. Despite his medical skills, his rude manner alienates locals as he battles hidden phobias and struggles with personal connections.
What to Expect When You Watch
Episodes run about 60 minutes, which keeps the pace tight, the full run covers 13 episodes, spread across 2 seasons and it leans into its comedy/drama roots while leaving room for the quieter character beats.
Performance-wise the series leans on Josh Charles, Abigail Spencer and Josh Segarra to carry the emotional weight, with the rest of the ensemble filling out the world around them.
Cast and Creative Team
Josh Charles, Abigail Spencer, Josh Segarra, Annie Potts, Cree and Stephen Spinella lead the cast.
Key roles include Josh Charles as Dr. Martin Best; Abigail Spencer as Louisa Gavin; Josh Segarra as Sheriff Mark Mylow; Annie Potts as Aunt Sarah; Cree as Elaine Denton.
Why It Stands Out
Fans of comedy, drama and medical have a clear reason to give this one a shot. It sits comfortably alongside FOX’s other originals, a 6.1/10 audience score puts it in steady company and it commits to its premise instead of hedging between tones.
Released in 2026 and carried by FOX with the series still running, it lands hardest with comedy and drama viewers.
How Best Medicine Compares
If Best Medicine lands for you, the next stops are Nathan for You, Taskmaster and Seinfeld, which share its comedy/drama lean.
Each of those sits at a different point on the same spectrum, so they make a natural follow-up once you finish the run here.
Where to Stream
Best Medicine comes from FOX. Check your preferred platform for current availability, since regional rights move around.
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On the whole Best Medicine is the kind of series that rewards a patient watch, with Josh Charles and Abigail Spencer doing the heaviest lifting, a tone that stays true to its comedy/drama roots, It has held up since 2026 and so if the premise sounds like your lane, the execution holds up.
The Bottom Line
Best Medicine is a safe bet for anyone already inside the comedy and drama lane, at 13 episodes it is an easy run to work through, the audience score holds around 6.1/10 and so there is little risk in starting it tonight.
Verdict: 6.1/10. Watch it if you want comedy/drama you can settle into.
