Show Guide

Common Side Effects

2025 Adult Swim Running 30 min Drama, Comedy, Thriller
8.5our take /10
7.8IMDb /10
Common Side Effects  follows former high school lab partners Marshall and Frances who begin to unravel a conspiracy involving big pharma and the federal government to suppress knowledge of a rare mushroom that may hold the key to curing all the world's disease

Our Review

From the Scavengers Reign creators: a conspiracy thriller about a mushroom — a blue fungus that can regrow tissue and cure disease — and the pharmaceutical machine that will burn the world to keep it off the market. Marshall (Dave King), the mycologist hiding with the cure, becomes the most wanted man alive; two DEA agents (and the… — the… — a pharma executive (their… — the show’s antagonist layer is written with real sympathy: the people killing the cure believe they’re saving the system that saves lives) chase him across a beautifully rendered America.

The absurdist comedy (the corporate-speak villainy, the… — the mycology-nerd authenticity, and the… — balances the paranoia thriller, and the animation carries the same organic-awe sensibility that made Scavengers special. The best new adult animation of the year.

Verdict: Watch it. A thriller about who owns the cure — gorgeous, funny, and furious.

Seasons

Common Side Effects — Season 1

10 episodes
Season 1 of Common Side Effects premiered 2025-02-02 and ran 10 episodes through 2025-03-30.